Description
Indole-3-Carbinol (I3C): A Dynamic Dietary Indole
Indole-3-Carbinol (I3C) is a naturally occurring compound found in cruciferous vegetables and is known for its complexity. Once ingested, I3C breaks down in the stomach and gut into a wide range of active metabolites—including DIM, ICZ, CT, Ascorbigen, and many others. This unique spectrum of derivatives is being explored across a variety of wellness-related applications.
I3C is frequently studied in relation to hormonal balance, detox-related pathways, and nutritional support for both men and women. It’s also of interest in areas involving methylation and nutrient metabolism.
Top Areas of Interest and investigation
- Hormonal balance and regulation
- Cervical wellness
- Breast health routines
- Prostate support
- Male wellness and fitness routines (testosterone–estrogen balance)
- Papillomavirus-related research focus
- Methylation and nutrient metabolism
What Are Dietary Indoles?
Dietary indoles are naturally occurring phytonutrients most commonly found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. Known for their unique biochemical properties, indoles continue to be studied for their diverse interactions within the body and their role in supporting overall wellness. Interesting fact: Theranaturals first coined the term Dietary Indoles in 1995—a name that has since become widely recognized.
Suggested Use:
For best results, take 3–4 capsules daily. Consistent, long-term use is recommended to maintain optimal support, particularly with age.
Tip: If you experience gas or bloating when taking the full dose at once, consider dividing your intake throughout the day with meals—for example, 1–2 capsules with breakfast, lunch, or dinner.
Note: A strong natural aroma is normal and may vary slightly from batch to batch due to the organic nature of the ingredients. For optimal stability, store in a cool, dry place away from direct heat and sunlight. The amber bottle helps protect the contents from light exposure and supports product longevity. When stored properly, shelf life is typically 3–5 years.
Warning: Due to potential hormonal activity, consult your healthcare provider before use if you are pregnant or lactating. Not recommended for individuals undergoing chemotherapy or radiation therapy.
Common Areas of Interest: PMS and menstrual cycle support, Menopause and postmenopausal wellness, Breast and lung-related routines, Cervical and genital health focus, RRP-related research interest, Adrenal and thyroid function support, Fibromyalgia-related wellness practices, Methylation and detox pathways, Prostate wellness, Estrogen–testosterone balance
Other Names: 3-Hydroxymethyl Indole, 3 Hydroxymethyl Indole, I3C, Indole 3 Carbinol, 3-(hydroxymethyl), 3-(hydroxyméthyl), 3 (hydroxymethyl) Indole, 3-Indolylcarbinol, 3 Indolylcarbinol, 3-Indolylmethanol, 3 Indolylmethanol, Indol-3-Carbinol, Indole, Indole 3 Carbinol, Indole-3-methanol, Indole-3-méthanol.
Helena Patterson –
Ms.
What are the side effects?
M Parish –
Side effects are generally related to gas or bloating. To mitigate this, you simple split up your dosing throughout the day and take with food.
Judy –
Judy
Dr. Bell recommended I take two a day a I have had cervical cancer previously and my paps and other procedures have not come back normal…I am hoping by taking this it will at least not get worse…my only complaint is this along with many of my other medications add up pricewise… but what does one do??
Renee Duncan –
A life saver
The I3C caps have worked a miracle for me. After my appendix was removed I was diagnosed with endrometriosis. The specialist was recommending surgery but wanted to wait for my body to health from the other surgery so the doctors all agreed and said they would retest in 6 months. During that time I started taking I3C and have taking 4 pills a day. Just had the follow up test and the doctors were amazed. My lining went ftom 8 mil to 6 mil. Normal is 4 for my age of 66. They said I should keep taking it and we will retest in another 6 months. This pill has truly made a major difference in my life.
Sarah Pastian –
an amazing product
I’ve been using I3C caps for over 8 years. My situation is unique and am doing great…I was introduced to this product by Dr Marie Bell, my OBGYN. I will visit with anyone who might be skeptical. I’m 68 yrs old, and KNOW this product to have helped me alot.
Taz –
I started taking this back in 2007 for an abnormal Pap. My doctor at the time suggested this product and it cleared everything. I stopped taking it for a few years as all was fine. But just got the news that my old problems started again…so starting this protocol again. I love this.
Sylvia hairston (verified owner) –
Great product be using for at least 20years or more after first child. I was diagnosed with abnormal paps and was having to have more frequent paps done after 2years of no abnormal paps I have been back to a normal schedule with no abnormalities thanks to this product. Like all I was introduced by a Germany specialist when I was at the cancer center for the abnormal paps in the early 2000’s as this was just starting to utilized. She which I wish I knew whom she was stepped in after the doctor wanted to do laser (leap) removal of abnormal cells, thankful she did. She gave me the information to this site and I have been purchasing from them every since. Throughout my years I will stop taking but will restart after a month or 2 but has been on a positive journey with clear paps for over 20 years.